With ever more challenging (T, p) environments for cementing applications in oil and gas wells, there is a need to change the classical paradigm of constitutive modeling of the early-age behavior of cementitious materials in oil-and gas well applications. Herein, we propose a bottom-up approach, which starts at the molecular scale of calcium-silicate-hydrates (C-S-H), and propagates this understanding via incremental poroelastic upscaling methods to the meso-and macroscale, and ultimately to the scale of engineering applications. With a clear focus on engineering risk-of-fracture evaluations, we show how to integrate this bottom-up approach with fracture mechanics.